Кафедра медичної та біоорганічної хімії
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Item Perspective pharmaceutical composition of coxib with caffeine – experimental studies of mnestic activity of rats in conditions of formaline edema(International Science Group, 2023-08) Syrova, Ganna; Lukianova, Larysa; Prysiazhnyi, Oleksandr; Krasnikova, JuliaItem Anti-Inflammatory Effect of Coxibs and their Compositions with Caffeine on the Level of Conjugated Dienes in the Formalin-Induced Edema Model(Turkish Chemical Society, 2022) Syrova, Ganna; Petiunina, Valentina; Savelieva, Olena; Tishakova, Tetyana; Lukianova, LarysaThe development of novel pharmaceutical compositions, which are effective in the treatment of different inflammatory diseases and have a minimum number of side effects is very relevant. The aim of the present study was biochemical confirmation of anti-inflammatory activity of new pharmaceutical compositions comprising coxibs and caffeine. The level of conjugated dienes as primary products of lipid peroxidation has been evaluated in the plasma of rats at the acute inflammation caused by formalin. The white male rats of WAG line were used. The content of conjugated dienes was determined by spectrophotometric method. It was shown that combinations of caffeine and coxibs showed statistical significant decrease in the content of conjugated dienes in the rats’ blood plasma. Caffeine enriched anti-inflammatory action of coxibs effectively.Item Students Science(ХНМУ, 2021-10-27) Syrova, Ganna; Lukianova, Larysa; Haychuk, AlesyaItem Learning Through Research(2021-05-21) Syrova, Ganna; Petiunina, Valentina; Lukianova, LarysaItem Unity of education and scientific research – the main principle of kharkiv national medical university(CPN Publishing Group, 2021-04) Syrova, Ganna Olegivna; Lukianova, Larysa; Petiunina, Valentina MikolaevnaItem Investigation of the influence of the pharmaceutical composition of celecoxib with licopid on the mnestic activity of rats under conditions of formalin edema(Cognum Publishing House. London, 2021-02) Syrova, Ganna; Lukianova, Larysa; Prysiazhnyi, Oleksandr; Synelnyk, V'yacheslav; Haychuk, AlesyaItem The role of laboratory practicum in the discipline "Analytical Chemistry" for students of speciality "Technologies of Medical Diagnostics and Treatment"(ХНМУ, 2020-11) Syrova, Ganna; Savel’eva, Olena; Lukianova, LarysaItem Thalassotherapy(НТУ «ХПІ», 2020-10) Syrova, Ganna; Makarov, Volodymyr; Lukianova, LarysaItem Investigation of the Peripheral Analgesic Activity of Oxicams and Their Combinations with Caffeine(Turkish Journal of Pharmaceutical Siences, 2020-08) Syrova, Anna; Lukianova, Larysa; Kozub, Svitlana; Zavada, Oksana; Levashova, Olga; Shaposhnik, ViktorItem How Thalictrum Foetidum extract influences the lipid peroxide oxidation and antioxidant system in rats subjected to chronic immobilisation stress(National Academy of Sciences of the Republic of Kazakhstan, 2020-06) Savelyeva, Elena; Vladimirova, Inna; Lukianova, Larysa