Кафедра медичної та біоорганічної хімії

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Author: search.filters.author.Макаров, Володимир ОлександровичSubject: search.filters.subject.immunоlogical and physiological parameters

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    Особливості визначення лабораторних критеріїв прогнозування лімфореї після мастектомії
    (2019) Макаров, Віталій Володимирович; Цівенко, Олександр Іванович; Сирова, Ганна Олегівна; Макаров, Володимир Олександрович
    Postoperative period after surgical interventions on the breast are determined by the level of physiological reserve and by the statement of immunоlogical and physiological parameters. The purpose of this research was to determine the risk prediction of postmastectomy lymphorrhea markers. A retrospective analysis of laboratories results of 78 patients with breast cancer after mastectomy during 2006 till 2011 years was made. Group I included patients without postoperative lymphorrhea. Group II included patients with prolongated postoperative lymphorrhea. Before operation patients of the II group had: PhI level decrease (73,1 ± 9,0), PhA level increase (4,3 ± 0,4) and higher, level decrease of completion of index of phagocytosis (0,8 ± 0,08), CRP rate increase (4,1 ± 3,34). In the early postoperative period patients of the II group had: the preservation of downward trends the PhI and PhA level increase, level decrease of completion of index of phagocytosis (0,8 ± 0,08), CRP rate increase +25% and more. In the early postoperative period patients of the I group had normal phagocytosis activity parameters and tendency to normalization of the PhA level. Using advanced laboratory researches in patients with breast cancer to determine the risk prediction of markers of postmastectomy lymphorrhea allows the use of additional preventive and curative interventions in the future.