Наукові роботи молодих вчених. Кафедра внутрішньої медицини № 3 та ендокринології
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Publication A clinical case of extraintestinal manifestations of ulcerative colitis(2023) Satapathy, Ayusha; Oliinyk, MariiaThe problem of treatment of inflammatory bowel diseases is relevant today. According to the International Research Committee, the incidence of ulcerative colitis (UC) has been steadily increasing in all countries in recent years. Arthritis develops in 20% of UC patients and is characterized by the involvement of a small number of large joints. Changes in the joints are usually completely reversible, but relapses are possible, the occurrence of which can be associated with an exacerbation of the underlying disease.Publication A clinical case of Schmidt syndrome(2023) Oliinyk, Mariia; Okhaigbe, Daniel OshokeSchmidt syndrome [also known as autoimmune polyendocrine syndrome type 2 (APS-2) is a term used to refer to a number of autoimmune disorders (primary adrenal insufficiency, hypothyroidism and type 1 diabetes mellitus) as a whole rather than a single illness.Item The level of visfatin and indicators of carbohydrate and lipid metabolism in postmenopausal women with the combined pathology of type 2 diabetes and osteoarthritis(2022) Cherpita, Valentyna; Zhuravlyova, LarysaPurpose: to determine the interdependence of indicators of glucose metabolism and lipid metabolism with levels of visfatin (VF) in women with T2DM and OA in pre- and postmenopause.Item Ways to optimize the treatment of biliary system disorders in patients with type 2 diabetes(2020) Tymoshenko, GalynaThe aim is to evaluate the effectiveness of complex therapy involving ursodeoxycholic acid and α-lipoic acid in patients with a combination of type 2 diabetes mellitus and chronic noncalculous cholecystitis based on the study of the dynamics of cholecystosonography parameters (in examination and the dynamic variants).Item Significance of metabolic parameters in patients with type 2 diabetes mellitus and chronic pancreatitis in forecasting the level of vaspin(2020) Pylov, DanielAdipokines are closely associated with the development of diseases and conditions such as type 2 diabetes mellitus, dyslipidemia, hypertension, atherosclerosis and inflammation, as they contribute to the development of insulin resistance, metabolic disorders, stimulate local inflammation and may affect atherogenesis process. Vaspin, a new serine protease inhibitor produced by visceral adipose tissue is an adipokine with insulin-sensitive and anti-inflammatory properties and has angio- and cardioprotective effects.Publication The relationship of muscle strength and osteoarthritis in women(2020) Olkhovska, Sofiia; Oliinyk, MariiaEpidemiological studies demonstrate the high prevalence of osteoarthritis in the population. Thus, the frequency of OA of large (supporting) joints in people older than 65 years varies from 19.2 to 50%. The leading role in maintaining the stability of the joints belongs to the muscles that hold them in a physiological position and provide, together with the ligaments and capsule, full functioning. Degenerative changes in muscle fibers associated with aging underlie the development of sarcopenia.Item Structure and frequency of comorbid pathology in cholelithiasis(2020) Kovalenko, Anastasiia; Kumechko, Oleksandra; Sikalo, YuliiaCholelithiasis is a common gastroenterological pathology in a population characterized by increasing morbidity and is one of the main causes of hospitalization of patients. It is known that hypercholesterolemia, as an important pathogenetic marker of cholelithiasis, is a component of metabolic syndrome, and associated pathological conditions. Therefore, the search for comorbidity is of particular interest to further prediction of the course and choice of treatment methods and prevention of exacerbations.Item Clinical case review on idiopathic pulmonary fibrosis(2020) Hossam, Bajbouj; Alkassab, Lila; Yankevych, OleksandrThe study covered a 62 years old female patient. The patient suffered from fatigue, dry cough, shortness of breath with moderate exercise, and intermittent discomfort in the heart. She had a history of recurrent pneumonia for 3 years that was later on treated and increased BP to a maximum of 160/90 mmHg. An angiogram and a high-resolution computed tomography (HRCT) of the lungs were conducted.Item Relationship between sleep status and the type 2 diabetes course(2020) Baskakova, Anastasiia; Sikalo, YuliiaType 2 diabetes mellitus is a current disease and a priority problem of the global health care system, given the steady growth of its prevalence. Since 2016, more than 2 million patients with DMhave registered in Ukraine, 90% are patients with type 2 diabetes mellitus. According to a report by the World Health Organization, type 2 diabetes mellitus is one of the four priority noncommunicable diseases included in the Global Action Plan for the Prevention and Control. At the present stage, the algorithm for combating type 2 diabetes mellitus involves, above all, early diagnosis and detection of relatively healthy population risk factors, their correction, as well as dynamic control of carbohydrate metabolism.Item Effect of lyraglutide on the lipid profile in patients with type 2 diabetes(2020) Amarachi, Adaeze Uzoma; Sokolnikova, NeliaType 2 diabetes mellitus is a complex metabolic disorder which characterized be carbohydrate, protein and lipid metabolism disorder due to target tissue resistance to insulin and its cellular metabolic effect. Obesity-dependent diabetes can significantly decrease life expectance. Diabetes mellitus type 2 accounts for about 90% to 95% of cases and the recent explosion of diabetes has aggravated insulin resistance and contributed greatly to the diabetes epidemic. Excess fat causes cells to be less responsive to insulin. In obese individuals, adipose tissue secretes excess of non-esterified fatty acids and other substances that affect metabolism such as glycerol, hormones, proinflammatory cytokines, leptin and others.