The use of ultrasound for obtaining pharmaceutical grade sodium chloride
Date
2016
Authors
Yurchenko, Oleg
Kalinenko, Olga
Baklanov, Olexandr
Baklanova, Larisa
Journal Title
Journal ISSN
Volume Title
Publisher
Lviv Polytechnic National University, Lviv, Ukraine
Abstract
The use of ultrasound (US) in the preparation of
pharmaceutical grade (PG) sodium chloride by the
sampling of final product from a vacuum evaporator
during the process of obtaining the “Extra” class table salt
at the crystallization stage of the sodium chloride has been
investigated. The US had been used: 1) for the content
control of the base matter – sodium chloride in the stock –
natural brine (sonoluminescent spectroscopy method). It is
necessary to create the appropriate crystallization
conditions by the control of the vacuum evaporator
parameters – temperature and pressure; 2) at the
crystallization stage of the sodium chloride to reduce the
co-crystallization between the sodium chloride and the
sulfate ions. It has been shown that the use of US allows
reducing the sulfate ions content in the final product and
getting sodium chloride PG satisfying the requirements of
pharmacopoeia standard (PS) 42-2572-88.
Description
Keywords
sodium chloride PG, ultrasound, table salt, sonoluminescent spectroscopy method
Citation
The use of ultrasound for obtaining pharmaceutical grade sodium chloride / O. Yurchenko, O. Kalinenko, O. Baklanov, L. Baklanova // Chemistry & chemical technology. – 2016. – Vol. 10, № 3. – P. 337–341.