Creation of anti-inflammatory pharmaceutical compositions (review)
Date
2022-11-13
Authors
Syrova, Ganna
Petyunina, Valentina
Makarov, Volodimir
Lukіаnova, Larysa
Chalenko, Natalia
Journal Title
Journal ISSN
Volume Title
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Abstract
The review article summarizes the data of literature and our own research on the creation of more effective and safe domestic combined drugs with a pronounced anti-inflammatory and analgesic effect. Untimely treatment of inflammatory processes often leads to long-term incapacity and even disability, so today there is an active search for new effective and safe domestic combination drugs with pronounced anti-inflammatory and analgesic effects. Due to the constant search for innovative drugs the treatment of a significant number of diseases and pathological conditions with existing drugs remains ineffective or causes addiction and a large number of side effects. As a result, inflammatory processes can be accompanied by severe pain, spasms, increased convulsive activity of the brain, other disorders, so non-narcotic analgesics and nonsteroidal anti-inflammatory drugs are combined with other agents that can cause complementary effects or potentiate each other's effects. Caffeine is a useful adjuvant of nonsteroidal anti-inflammatory drugs of various chemical structures in terms of anti-inflammatory and analgesic effects. The article presents a literature review of the current state of treatment of inflammation and pain, conducting research to expand the therapeutic capabilities of known pharmaceuticals, the creation of pharmaceutical compositions of nonsteroidal anti-inflammatory drugs with caffeine.
Description
Keywords
pain, inflammation, caffeine, non-narcotic analgesics, nonsteroidal anti-inflammatory drugs, pharmaceutical composition
Citation
Creation of anti-inflammatory pharmaceutical compositions (review) / G. O. Syrova, V. M. Petyunina, V. O. Makarov, L. V. Lukianova, N. M. Chalenko // Inter Collegas. – 2022. – Vol. 9, No 1. – P. 93 –101.