Effect of Surface Modification of Sputtered Ta2O5 Magnetron Ceramic Coatings on the Functional Properties of Antigen-Presenting Cells In Vitro Tests

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2020

Authors

Yakovin, S.
Dudin, S.
Zykova, A.
Safonov, V.
Goltsev, A.
Dubrava, T.
Rassokha, I.

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Abstract

The effect of surface treatment of Ta2O5 nanostructured coatings by argon ions and electron beam on the functional potential of antigen-presenting cells of the monocyte-phagocytic system has been studied. The adhesive potential, indicators of phagocytic and metabolic activity of the studied cells depending on the surface properties of magnetron sputtered tantalum pentoxide coatings were analyzed. Electron irradiation process led to the stimulation of adhesive potential, phagocytic and metabolic activity of cells on the Ta2O5 coated surfaces. On the contrary, the surface treatment by argon ions significantly reduced the functional activity of the studied cells

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Keywords

Antigen-Presenting Cells, Sputtered Ta2O5 Magnetron Ceramic Coatings, In Vitro tests

Citation

Effect of Surface Modification of Sputtered Ta2O5 Magnetron Ceramic Coatings on the Functional Properties of Antigen-Presenting Cells In Vitro Tests [Electronic resource] / S. Yakovin, S. Dudin, A. Zykova, V. Safonov, A. Goltcev, T. Dubrava, I. Rassokha // Nanomaterials in Biomedical Application and Biosensors (NAP-2019) [eBook] / A. D. Pogrebnjak, M. Pogorielov, R. Viter. – Р. 151–159. – (Springer Proceedings in Physics book series. Volume 244). – Access mode: https://doi.org/10.1007/978-981-15-3996-1.

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