Кафедра акушерства та гінекології № 2
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Item Dostarlimab for primary advanced or recurrent (A/R) endometrial cancer (EC): Outcomes by blinded independent central review (BICR) of the RUBY trial (ENGOT-EN6-NSGO/GOG-3031/RUBY).(2023) Powell, Matthew A.; Hietanen, Sakari; Coleman, Robert L.; Monk, Bradley J.; Zub, Oleksandr; O'Malley, David M.; Gilbert, Lucy; Podzielinski, Iwona; Angioli, RobertoПацієнти (пацієнти) з первинною прогресуючою стадією III або IV або першим рецидивним раком ендометрыю були рандомізовані 1:1 для отримання достарлімабу 500 мг або PBO плюс карбоплатину AUC 5 і паклітакселу 175 мг/м2 Q3W (6 циклів), потім достарлімабу 1000 мг , або PBO, монотерапія Q6W до 3 років.Item State of hemostasis system in patients with thrombophilia and failed attempts of in vitro fertilization in anamnesis(2021) Khushboo, Кalani; Tarawneh, DianaIn vitro fertilization (IVF) is one of the most modern and promising methods of infertility treatment. Due to the widespread use of assisted reproductive 190 technologies (ART), the issue of improving their efficiency becomes especially relevant. This study objective was to determine a state of hemostasis system and pathophysiological mechanisms of thrombosis development in patients with genetic and acquired thrombophilia.Item Peculiarities of tactics of managing women with prolongetal hypokinesia using combined oral contracepts(2021) Aboelnour, LinaLimiting the amount of muscle activity is a common phenomenon in modern society, gaining new relevance during the period of quarantine measures, when the work acquired a remote character with the active use of computer technology. However, at this stage in their lives, women of reproductive age still use combined oral contraceptives (COCs) to protect themselves from unwanted pregnancies.Item Cyclic mastodynia in medical university students and ways of its corrections(2020-01-22) Yuntsova, KaterynaIn the complex treatment of cyclic mastodynia resulting from stress, it is necessary to include a herbal preparation, which can reduce its symptoms, and in some cases, completely level it.Item Methods of early diagnostic of adenomyosis(2020-01-22) Ahmed, Ahmed Mosad GaballaEvidence of increased expression of Ki-67 proliferation protein and intensification of the neovascularization process in endometrial biopsies with underlying myometrium in adenomyosis and under conditions of combination of adenomyosis with hyperplastic processes, endometrial, be used as a diagnostic in detecting adenomyosis, including associated with hyperplastic endometrial processes. 3D ultrasound with the definition of uterine junctional zone is an effective method of noninvasive diagnosis of adenomyosis.Item Важливість методів діагностики церебро-васкулярних порушень у вагітних жінок(2020-05-22) Абдуллаєва, Нубар Азад кизи; Запорожченко, Єлизавета СергіївнаНа підставі перелікованих досліджень можуть бути вдосконалені критерії діагностики та комплексної терапії вагітних з ЦВП, що буде сприяти зниженню можливих ускладнень вагітності. Удосконалення алгоритму діагностичних і терапевтичних заходів будуть направлені для зменшення або усунення ознак ЦВП раннього гестозу, шляхом корекції порушень мозкового та матково-плодового кровотоку, ендотеліальної дисфункції, що буде сприяти зниженню материнської та перинатальної захворюванності і смертності.Item Methods of achieving normoovulation in patients with polycystic ovarian syndrom(2020-05-22) Shaikh, Aliyanoor; Gradil, OksanaThe results of a study in patients with PCOS show that treatment with metformin leads to a healthier carbohydrate metabolism, possibly by reducing the amount of visceral fat than in the treatment with oral contraceptives, and to the normalisation of the menstrual cycle/Item Managing insulin resistance in woman with polycistic ovarian syndrom(2020-05-22) Okwuwolu, Chimakarum Sarema; Gradil, OksanaIn the pathophysiology of PCOS, the role of insulin resistance cannot be overemphasized. To this effect, It is our opinion that managing the insulin resistance is the best pathogenetic means of treating chronic PCOS as it has gynecologic and metabolic benefits.Item The modern aspects of management of patients with ectopic pregnancy(2020-05-22) Agbenu, Sedem; Gradil, OksanaEctopic pregnancy is very manageable.US helps in the diagnosis with surgical treatment and it is still very effective and helpful although laparotomy is gradually fading out the use of laparoscopic surgery because is more conservative and less invasive.Item Preventive criteria of cervical cancer(2020-05-22) Aboelnour, LinaIn developed countries, programmes are in place which enables girls to be vaccinated against HPV and ladies to induce screened regularly. Screening allows pre-cancerous lesions to be identified at stages once they'll easily be treated. Early diagnosis precludes up to 80% of cervical cancer cases in these nations. In developing countries, there is very little access to such preventive steps, and cervical cancer is usually not diagnosed until it is further advanced and symptoms can develop.. Besides, access to treatment of such late-stage disease (for example, cancer su . In developing countries, there's limited access to those preventative measures and cervical cancer is usually not identified until it's further advanced and symptoms develop. Besides, access to treatment of such late-stage disease (for example, cancer su.).