Кафедра акушерства та гінекології № 2
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Item Endoscopy in gynecology : guidelines for practical training(2025) Lazurenko, V.; Ovcharenko, O.; Lyashchenko, O.; Safonov, R.Protection of women's reproductive health is one of the important problems of health care of the population of Ukraine. Wide use of endoscopic methods in the practice of an obstetrician-gynecologist allows early diagnosis and treatment of many gynecological diseases.Item Endoscopy in gynecology: methodical guidelines for students’ independent classroom work(2025) Lazurenko, V.; Ovcharenko, O.; Lyashchenko, O.; Tishchenko, O.Purpose: acquiring knowledge and skills for solving professional tasks and providing planned and emergency medical care using endoscopic operative methods of treatment in obstetrics and gynecology, studying the anatomical aspects of gynecological endoscopy; to know the main legal documents regulating the performance of endoscopic operations.Item Endoscopy in gynecology : methodical guidelines for students' independent extracurricular work(2025) Lazurenko, V.; Ovcharenko, O.; Lyashchenko, O.; Bilyi, Ye.Protection of women's reproductive health is one of the important problems of the health care of the population of Ukraine. Wide use of endoscopic methods in the practice of an obstetrician-gynecologist allows early diagnosis and treatment of many gynecological diseases. Endoscopic methods is a minimally invasive surgical intervention that minimizes the negative impact on the organs of the reproductive system in women.Item Eryptosis contributes to gestational diabetes mellitus in maternal obesity(2024) Лазуренко, Вікторія Валентинівна; Железняков, Олександр Юрійович; Прокопюк Володимир Юрійович; Lazurenko, V.; Zhelezniakov, O.; Prokopiuk, V.Obesity is considered to be a risk factor for Gestational Diabetes Mellitus, which is characterised by hyperglycaemia in pregnant women. Recent studies have demonstrated that glycated erythrocytes are more prone to eryptosis, a unique regulated cell death observed only in mature erythrocytes.Item Cesarian section in Ukraine and the United Kingdom: semilarities and differences(2024) Лазуренко, Виктория Валентиновна; Железняков, Олександр Юрійович; Алхімов Сергій Юрійович; Овчаренко Ольга Борисівна; Сафонов, Роман Анатолійович; Тертишнік, Деніс Юрійович; Lazurenko, V.; Zhelezniakov, O.; Alkhimov, S.; Ovcharenko, O.; Safonov, R.; Tertyshnyk, D.Negative statistics reveal that the increase in the frequency of CS is typical not only for the UK, but also for Ukraine, although in Ukraine the explanation for this situation is the increase in the frequency of obstetric and extragenital pathology during martial law, and in the UK it is the woman’s choice. Understanding the differences between countries in their approaches to CS will help improve the quality of medical care and optimize outcomes for both mother and newborn.Item Eryptosis as a link between bacterial reproductive tract infection and anemia in pregnant women(2024) Кудін, Ілля Дмитрович; Лазуренко, Вікторія Валентинівна; Прокопюк, Володимир Юрійович; Железняков, Олександр Юрійович; Панасовський, Микола Леонідович; Kudin, I.; Lazurenko, V.; Prokopiuk, V.; Zhelezniakov, O.; Panasovskyi, M.Інфекції репродуктивного тракту бактеріального походження у вагітних жінок пов’язані з прискоренням процесів ериптозу, який може призводити до анемії у цих вагітних. Виключно при бактеріальній інфекції генітального тракту було показано, що запускається с кремблування із цього часу ериптоз в еритроцитах вагітних жінок.Item Some manifistarion of cerebpovascular diseases in pregnant women(ХНМУ, 2023-02-13) Saswat, Sasmal; Rajnandini, Sharma; Abdullaieva, NubarAccording to some studies and data provided by PubMed.gov on, Cerebrovascular Disease (CVD) during pregnancy, it was found that, preeclampsia has a burden of around 10 million cases annually, appear not only during pregnancy, but also in the postpartum period. Hypertension in pregnancy which escalates to preeclampsia is the most commonly seen CVD abnormality in pregnant women. Acute cerebrovascular disorders, including posterior reversible encephalopathy syndrome (PRES), reversible cerebral vasoconstriction syndrome (RCVS), ischemic and hemorrhagic stroke, and cerebral venous sinus thrombosis (CVST) are severe complications of preeclampsia that can result in permanent maternal disability or death, so it needs to be managed timely and precisely. An increase in blood pressure from early pregnancy indicates the development of preeclampsia and may be a predictor of cerebrovascular disorders.Item Features of preconception preparetion of women with endometriomas(ХНМУ, 2023-02-13) Okhaigbe, Daniel OshokeEndometriosis is one of the causes of primary infertility. Most often, the diagnosis of endometriosis is established in the presence of endometrioid ovarian cysts, which are treated by surgical or conservative treatment with the staged usage of hormonal or anti-inflammatory drugs. Based on the work we have done, we came to the conclusion that the presence of endometriomas significantly affects the ovarian reserve and there is a risk of developing infertility of ovarian origin. When endometriomas are detected in women of reproductive age, careful monitoring of the ovarian reserve is necessary. With a decrease in anti-Müllerian hormone, it is recommended that the woman immediately implement the fertile function, and in the absence of such an opportunity, cryopreservation of oocytesItem Redox status and cell membrane alterations of circulating leukocytes and erythrocytes in abnormal uterine bleeding(2023-03-15) Alieksieieva, Olena; Harkavenko, Karyna; Posokhov, Evgeny; Prokopiuk, Volodymyr; Lazurenko, Viktoriia; Safonov, RomanAim. To analyze the eryptosis degree, the state of cell membranes and redox status of circulating red blood cells and leukocytes in patients with abnormal uterine bleeding and its combination with hypothyroidism. Materials and methods. Patients, 74 women aged 18 to 49 years, were examined, which were divided into 3 groups: group I — women with abnormal uterine bleeding (AUB) (24 patients); group II — with AUB and thyroid pathology (30 patients, of whom 18 women had primary hypothyroidism and 2 — secondary hypothyroidism); group III — control group (20 healthy women, who had never had menstrual irregularities). Eryptosis of circulating erythrocytes was assessed by flow cytometry using annexin V staining and 2′,7′-dichlorodihydrofluorescein diacetate (H2DCFDA) staining. Fluorescent probes O1O (2-(2¢-hydroxy-phenyl)-5-phe-nyl-1,3-oxazole) and PH7 (2-(2¢-hydroxy-phenyl)-phenanthro[9,10-d]-1,3-oxazole) were used to characterize changes in phospholipid bilayers of circulating erythrocytes and leukocytes. Lysed blood samples were stained with antibodies to CD45, 7-aminoactinomycin D and H2DCFDA to analyze the redox status of circulatingviable leukocytes.Item Modern view on chronic respiratory dieseases in pregnant (review).(2022-09-30) Lazurenko, Viktoriia; Bilyi, Evgeny; Liashchenko, Olga; Ovcharenko, Olga; Borzenko, IrynaDisorders in the fetoplacental complex of pregnant women with chronic respiratory diseases (CRD) include a wide range of problems in modern obstetrics in medical, economic and social aspects. Respiratory diseases in the context of disorders of the fetoplacental complex (FPC) may be a comorbid process, a background to the abnormal pregnancy, or a premorbid condition that contributes to the development of placental dysfunction (PD) or even initiates it; morphophysiological changes characteristic of pregnancy also affect the state of the respiratory system, moderating the course of bronchoobstructive diseases. Respiratory diseases in women, the impact of its treatment and features of the course and medical support of pregnancy in these conditions affect the condition of both the woman and the fetus, and physical and neuropsychological development of the child in future.