Наукові праці. Кафедра внутрішньої медицини № 1

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    Modern aspects of CHF and COPD concurrent course
    (2018-12) Zelena, Iryna; Kalashnyk, Yulia
    Growing burden of chronic obstructive pulmonary disease and chronic heart failure becomes a challenge for healthcare professionals. Aging, which is now present in most developed countries, brightens a problem of growing number of chronic life-long diseases [9]. That increases hospitalization rate due to acute states and exacerbations, increases workload for personnel, and influences patients’ life quality. On the other hand, even in ambulatory, excessive medications and life-affecting symptoms significantly reduce life quality, leading to development of anxiety and depression. In turn, those states are found to be worsening patients’ adherence to treatment and promote exacerbation and symptoms deterioration
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    Biomarkers usage in minimally invasive diagnosis of nonalcoholic steatohepatitis in nonalcoholic fatty liver disease patients
    (2017) Babak, Oleg; Molodan, Volodymyr; Lapshyna, Kateryna; Prosolenko, Kostyantyn
    Plasma CK-18 and FGF-21 levels are increased in patients with NASH and also associate with atherogenic dyslipidemia and impaired liver enzyme activity. Study plasma levels of CK-18 and FGF21 allows to establish the presence of NASH in patients with NAFLD. The findings suggest the possibility of using these biomarkers for minimally invasive screening diagnosis of NASH and represent the perspective of further research.