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Item Study of phenolic compounds of umbellate wintergreen herb and their influence on biochemical indicators of blood and urine in the rat model of chronic kidney disease(Science Rise: Pharmaceutical Science, 2024) Khodak, Larisa; Kovregin, Oleksiy; Mykhailenko, Olha; Yudkevich, Tetiana; Lytkin, Dmytro; Ivanauskas, Liudas; Vladymyrova, Inna; Starikov, VolodymyrDiseases of the kidneys and urinary tract are a common problem in people of all ages. Kidneys filter blood, removing water-soluble waste from the body, maintain water-salt balance, stabilize blood pressure and PH level. Intoxication, hypothermia, injuries and other causes lead to problems with the kidneys – inflammatory disease, urolithiasis, etc. Therefore, the development of effective herbal remedies that affect the etiopathogenic factors of diseases is urgent.Item Trauma of Urinary tract(2014) Savenkov, V.; Knigavko, OleksandrModern methods of diagnostic and treatment of trauma urinary tract are written.Item Relation of postmortem changes development and exact postmortem interval(2020) Grygorian, Edgar; Olkhovsky, Vasil; Gubin, MykolaPurpose: Precise postmortem interval evaluation is crucial in cases when violent types of death are suspected by a forensic medical examiner. There are different factors that could affect results of postmortem interval (PMI) evaluation by a forensic medical expert. The aim of this study was to investigate the relationship between the known postmortem time interval and the degree of particular postmortem changes development. Materials and Methods: A cross-sectional analysis of 116 forensic medical examinations of deceased persons (of them, 58 females and 58 males), in cases of non-violent death, was performed. The data about the time of death was obtained from police preliminary records provided to the examination - only the cases with known time of death were included in the study. Postmortem changes were evaluated by Total Body Score (TBS) [1] at equal time interval after death (48 hours ± 3 hours). Interconnection between postmortem changes degree and PMI was estimated using Spearman's rank correlation. Difference between sexes was evaluated using Mann-Whitney U test. Results: "Thickness of clothes" criterion reached the highest positive correlation coefficient, "ambient temperature" criterion had also a significant positive correlation. The rest of the studied criteria had very weak correlation with the development of postmortem changes. Conclusions: Several criteria had significant (p < 0.05), yet week, impact on the postmortem changes development. The other criteria were statistically insignificant.Item Dermatoglyphic features of the mеn's feet in different ciscarpathian ethno-territorial groups(2021) Gunas, I.; Dunaev, O.; Popadynets, O.; Kozovіy, R.; Kindrativ, E.In the course of the study, we analyzed the ridge, delta count and the frequency of dermatoglyphic parameters locatedon the plantar surfaces of the feet, studied the correlations between the pattern type and ridge and delta counts. It is esta blishedthat between dermatoglyphic signs of feet in men of different ethno-territorial groups of Prykarpattia (Boyks, Lemkos, Hutsuls)there are differences that allow to differentiate these ethno -territorial groups: Hutsuls have a low numerical value of the ridgecount, no whorl and high frequency of loop patterns; for Boykоs it is a low numerical value of the delta account and a lowfrequency of whorl patterns; for Lemkos it is a high numerical value of the ridge and delta account, a significant frequency ofwhorl patterns.Item Pharmaceutical terminology for English-medium students: Students’ guide(Kharkiv National Medical University, 2017) Lozenko, Viktoriia; Polyanskaya, HelenThe students’ guide is made up according to the syllabus of the course “Latin language and medical terminology”. The book contains the main aspects of pharmaceutical terminology: trivial names of medicines, prescription phrases, prescription.Item Taras Shevchenko. Biography facts(Харківський національний медичний університет, 2014-03-17) Samolysova, O.; Oluronbi, Olubunmi IfeoluThe main idea of this article is to acquaint foreign students with the founder of the modern Ukrainian literary languageItem Waist to height ratio in hypertensive patients(2015-09) Kochubiei, Oksana; Кочубєй, Оксана Анатоліївна; Кочубей, Оксана Анатольевна; Ковалева, Ольга Николаевна; Kovalyova, Olga; Ковальова, Ольга Миколаївна; Ashcheulova, Tetyana; Ащеулова, Тетяна Вадимівна; Ащеулова, Татьяна ВадимовнаOverweight and obesity are common pathological conditions in the adult population of Ukraine and are associated with other chronic diseases, including hypertension, diabetes and dyslipidemia. All these diseases are key factors modified risk for other diseases, such as cardiovascular and renal disease. Early detection of these conditions will help in controlling their strategy. The aim of our study was to investigate the association of waist to height ratio (WHtR) in conjunction with the parameters of lipid metabolism in hypertensive patients. Methods. 73 hypertensive patients were examined. All patients underwent complex clinical examination which included estimation of complaints, history taking, physical and additional methods of examination. Following anthropometric parameters (WHtR) and parameters of lipid metabolism were measured. Data is represented as Me (Q25-Q75). Kruskal-Wallis and median test were used, р <0,05. Results. The hypertensive patients are characterized by increased levels of total cholesterol 5,67 (4,96- 7,11) mmol/L, triglyceride 2,75 (2,56-3,01) mmol/L, low-density lipoprotein-cholesterol 0,98 (0,83-1,35) mmol/L and decreased levels of highdensity lipoprotein-cholesterol 3,51 (2,77-4,54) mmol/L. Obesity was observed in 86% of hypertensive patients as measured by WHtR ≥0,5, dyslipidemia was detected in 73% patients as measured by levels of total cholesterol. In correlation analysis positive relations between WHtR and levels of total cholesterol (R=0,42; р<0,05) in hypertensive patients were found. Conclusions. The hypertension is accompanied by dyslipidemia, characterized by increased levels of total cholesterol, triglyceride, low-density lipoprotein-cholesterol and decreased levels of highdensity lipoprotein-cholesterol. Significant positive relationships between WHtR and levels of total cholesterol in hypertensive patients were detected, which is another confirmation of the clinical significance of this measurement and substantiates the need for screening patients with WHtR in determining obesity, dyslipidemia and cardiovascular riskItem Analysis of heart rate variability as a potential marker of shock factors(2021-10-28) Pandikidis, N.; Maslova, Natalia; Maslova, YuliiaChanges in the functional state of the autonomic nervous system are accompanied by various functional states of the heart itself, as well as cardiac and non-cardiac diseases. Was conducted an analysis of the literature of recent years, the importance of analyzing heart rate variability in diagnosing various lesions of the central nervous system, as well as predicting the survival of patients.Item Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19(2023-08) Gavrylov, Anatoliy; Tieroshyn, Vadym; Wainstein, M.; Spyrison, Nicholas; Dai, Danyang; Ghadimi, Moji; Chávez-Iñiguez, Jonathan S.; Rizo-Topete, Lilia; Citarella, Barbara Wanjiru; Merson, Laura; Pole, Jason D.; Claure-Del, Granado Rolando; Johnson, David W.; Shrapnel, SallyIntroduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes.Item Architecture of a functional system of the sagittal balance maintaining(Polish Physiological Society, 2021-09-15) Goncharova, AlinaTo understand the mechanisms of maintaining the sagittal balance within physiological borders, it is important to consider it within the p.K. anokhin’s concept of functional system. Consideration of the structures involved in maintaining the sagittal balance from this point of view will allow us to determine the possible causes of its displacement and methods of its correction.