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Item Clinical case review on idiopathic pulmonary fibrosis(2020) Hossam, Bajbouj; Alkassab, Lila; Yankevych, OleksandrThe study covered a 62 years old female patient. The patient suffered from fatigue, dry cough, shortness of breath with moderate exercise, and intermittent discomfort in the heart. She had a history of recurrent pneumonia for 3 years that was later on treated and increased BP to a maximum of 160/90 mmHg. An angiogram and a high-resolution computed tomography (HRCT) of the lungs were conducted.Item The functional state of the hepatobiliary system in patients with rheumatoid arthritis(2015) Avodunmila, Oluvakayde; Abugu, NiadoniyaOne of the most common diseases of the musculoskeletal system is rheumatoid arthritis. In chronic disease observed violations of various types of exchanges, and prolonged use of drugs can have a negative impact on the various organs and systems, including biliary system.Item Significance of metabolic parameters in patients with type 2 diabetes mellitus and chronic pancreatitis in forecasting the level of vaspin(2020) Pylov, DanielAdipokines are closely associated with the development of diseases and conditions such as type 2 diabetes mellitus, dyslipidemia, hypertension, atherosclerosis and inflammation, as they contribute to the development of insulin resistance, metabolic disorders, stimulate local inflammation and may affect atherogenesis process. Vaspin, a new serine protease inhibitor produced by visceral adipose tissue is an adipokine with insulin-sensitive and anti-inflammatory properties and has angio- and cardioprotective effects.Item A systematic review of dapagliflozin treatment for patients with type 2 diabetes mellitus(2017) El-Hayek, MohamadNew class of drugs for treatment type 2 diabetes mellitus (T2DM) are sodium-glucose cotransporter 2 (SGLT2) inhibitors. These drug are an antihyperglycaemic agents with an insulin-independent mode of action. One of the SGLT2 inhibitors class that used in Ukraine for treatment patients with T2DM is a Dapagliflozin. We try to summarize current evidence from different clinical trials that assess the clinical efficacy and safety of dapagliflozin.Item Relationship between sleep status and the type 2 diabetes course(2020) Baskakova, Anastasiia; Sikalo, YuliiaType 2 diabetes mellitus is a current disease and a priority problem of the global health care system, given the steady growth of its prevalence. Since 2016, more than 2 million patients with DMhave registered in Ukraine, 90% are patients with type 2 diabetes mellitus. According to a report by the World Health Organization, type 2 diabetes mellitus is one of the four priority noncommunicable diseases included in the Global Action Plan for the Prevention and Control. At the present stage, the algorithm for combating type 2 diabetes mellitus involves, above all, early diagnosis and detection of relatively healthy population risk factors, their correction, as well as dynamic control of carbohydrate metabolism.Item Biological therapy in patients with Rheumatoid arthritis(2015) Исаак, Адора; Дуглас, Ибиба; Isaak, A.; Duglas, I.The foundation of modern biological therapy have significantly changed the whole system of treatment of rheumatic diseases, is the use of antagonists of tumor necrosis factor alpha (TNF-α). Drugs of this class are most relevant concepts of "disease-control" means, as to significantly reduce the direct manifestation of the disease and significantly inhibit joint destruction, leading to the development of disease remission with previously unattainable speed.Item The vitamin D in patients with osteoarthritis and type 2 diabetes mellitus(2020) Magapu, Veera Venkata AkhilThe aim of the study is to determine the level of vitamin D in patients with osteoarthritis and with the combination of osteoarthritis and type 2 diabetes mellitus and its effect on the course of type 2 diabetes mellitus and osteoarthritis.Item Effect of additional antioxidant therapy in patients with combine course of osteoarthritis and type 2 diabetes mellitus(2018) Nagiyeva, Aynur; Rybina, AnastasiiaThe aim of the present study to learn the influence of antioxidant therapy on the condition of patients with osteoarthritis (OA) in combination with type 2 diabetes mellitus (T2DM).Item Morphological changes in experimental tuberculosis resulting from treatment with quercetin and polyvinylpyrrolidone(2017) Бутова, Татьяна Сергеевна; Butova, Tetiana; Zaitseva, S.; Stepanenko, G.; Butov, DmytroAims and objectives. Morphological study of tissue necrosis stages in experimental organpreserving tuberculosis pharmacotherapy using Quercetin and Polyvinylpyrrolidone (QP).Item The usage of noninvasive diagnostic tests in patients with chronic liver diseases(2014) Ogneva, Olena; Zhuravlyova, AnnaLiver is one of the most affected organs in diabetes. Diagnosis of diffuse chronic liver diseases, especially on the early stages of progression of histological changes is rather complicated problem. The «gold» standard for diagnosing of histological changes in the liver is liver biopsy. However, this procedure is invasive, has contraindications and this method is not accurate enough. It was the basis for the introduction of noninvasive diagnostics of liver fibrosis into the clinical practice. The main are liver ultrasound, computerized tomography, magnetic resonance imaging and elastometry. Particular attention is paid to the new noninvasive diagnostic tests FibroTest and FibroMax.